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  • Adams J et al.  Pilot study of a moderate dose multivitamin/mineral supplement for children with autistic spectrum disorder.  Journal of Alternative and Complementary Medicine.  10(6):1033-1039, 2004.
  • Adams J et al. Analyses of toxic metals and essential minerals in the hair of Arizona children with autism and associated conditions, and their mothers. Biology Trace Element Research. 110(3):193-209, 2006.
  • Adams J. Summary of Biomedical Treatments for Autism. Autism Research Institute Publication. 40 (April), 2007.
  • Ah Kang-Yoon S et al.  Relation of short-term pyridoxine-hydrochloride supplementation to plasma vitamin-B6 vitamers and amino acid concentrations in young women.  American Journal of Clinical Nutrition.  55(4):865-872, 1992.
  • Ahmed, F., et al. Efficacy of Twice-Weekly Multiple Micronutrient Supplementation for Improving the Hemoglobin and Micronutrient Status of Anemic Adolescent Schoolgirls in Bangladesh. American Journal of Clinical Nutrition. 82:  829 – 835, 2005.
  • Alarcon, K., et al. Effects of Separate Delivery of Zinc or Zinc and Vitamin A on Hemoglobin Response, Growth, and Diarrhea in Young Peruvian Children Receiving Iron Therapy for Anemia.  American Journal of Clinical Nutrition. 80: 1276 – 1282, 2004.
  • Angley M et al. Children and autism--Part 2--management with complementary medicines and dietary interventions. Australian Family Physician. 36(10):827-30, 2007.
  • Anonymous. Vitamin B6 (pyridoxine and pyridoxal 5'-phosphate) - monograph. Alternative Medicine Review. 6(1):87-92, 2001. Review.
  • Audhya T. (2002, October).  Laboratory indices of vitamin and mineral deficiency in autism.  Paper presented at the Defeat Autism Now! Conference, San Diego, California.
  • Autism Research Institute. Accessed May and June 2008.
  • Baez-Saldana A et al.  Biotin deficiency induces changes in subpopulations of spleen lymphocytes in mice.  American Journal of Clinical Nutrition.  67(3):431-437, 1998.
  • Balogh, K., et al. Inhibition of Bacterial Growth in Human Saliva by Vitamins B1, B2, and B6. Journal of Dental Research. 36 (5): 886-891, 1960.
  • Baqui, A., et al. Simultaneous Weekly Supplementation of Iron and Zinc Is Associated with Lower Morbidity Due to Diarrhea and Acute Lower Respiratory Infection in Bangladeshi Infants. Journal of Nutrition. 133: 4150-4157, 2003.
  • Benton, D., et al.  Thiamine supplementation mood and cognitive functioning.  Psychopharmacology (Berlin).  129(1):66-71, 1997.
  • Bhandari, N., et al. Effect of Routine Zinc Supplementation on Pneumonia in Children Aged 6 Months to 3 Years: Randomized Controlled Trial in an Urban Slum. British Medical Journal. 324: 1358-1362, 2002.
  • Bhandari, N., et al. Substantial Reduction in Severe Diarrheal Morbidity by Daily Zinc Supplementation in Young North Indian Children. Pediatrics.  109: 86-92, 2002.
  • Black, M., et al. Iron and Zinc Supplementation Promote Motor Development and Exploratory Behavior Among Bangladeshi Infants. American Journal of Clinical Nutrition. 80: 903 – 910, 2004.
  • Brouwer, I., et al. Dietary Folate from Vegetables and Citrus Fruit Decreases Plasma Homocysteine Concentrations in Humans in a Dietary Controlled Trial.  Journal of Nutrition. 129: 1135-1139, 1999.
  • Bryan, J., et al. Short-Term Folate, Vitamin B-12 or Vitamin B-6 Supplementation Slightly Affects Memory Performance But Not Mood in Women of Various Ages. Journal of Nutrition. 132: 1345-1356, 2002.
  • Burton G et al.  Vitamin E:  Antioxidant activity, biokinetics, and bioavailability.  Annual Review Nutrition.  10:357-382, 1992.
  • Carter, l., et al. Self-Reported Calcium Intake and Bone Mineral Content in Children and Adolescents. Journal of the American College of Nutrition.  20: 502-509, 2001.
  • Chitchumroonchokchai, C., et al. Xanthophylls and  -Tocopherol Decrease UVB-Induced Lipid Peroxidation and Stress Signaling in Human Lens Epithelial Cells. Journal of Nutrition. 134: 3225-3232, 2004.
  • Clark J et al. Symptomatic vitamin A and D deficiencies in an eight-year-old with autism. JPEN Journal of Parenteral and Enteral Nutrition. 17:284-6. 1993.
  • DeAnn J et al.  Gut restoration and chronic disease.  Journal of the American Nutraceutical Association.  5(4):20-33, 2002.
  • Dietrich, T., et al. Association between Serum Concentrations of 25-Hydroxyvitamin D and Gingival Inflammation. American Journal of Clinical Nutrition. 82: 575 – 580, 2005.
  • Diliberto E et al. Multicompartmental secretion of ascorbate and its dual role in dopamine b-hydroxylation.  American Journal of Clinical Nutrition.  54(6 Supplement):1163S-72S, 1991.
  • Dodiuk-Gad, R. P., et al. Sustained Effect of Short-term Calcium Supplementation on Bone Mass in Adolescent Girls with Low Calcium Intake. American Journal of Clinical Nutrition. 81: 168 – 174, 2005.
  • Dolske M. et al.  A preliminary trial of ascorbic acid as supplemental therapy for autism.  Progress in Neuropsycho-pharmacology and Biological Psychiatry.  17(2):765-774, 1993.
  • Earnest, C., et al. Complex Multivitamin Supplementation Improves Homocysteine and Resistance to LDL-C Oxidation. Journal of the American College of Nutrition. 22: 400-407, 2003.
  • Engler, M. M., et al. Antioxidant Vitamins C and E Improve Endothelial Function in Children With Hyperlipidemia: Endothelial Assessment of Risk from Lipids in Youth (EARLY) Trial. Circulation. 108: 1059 – 1063, 2003.
  • Etten, E., et al. 1,25-Dihydroxycholecalciferol: Endocrinology Meets the Immune System.  Proceedings of the Nutrition Society.  61: 375-380, 2002.
  • Fernandez-Robredo, P., et al. Vitamins C and E Reduce Retinal Oxidative Stress and Nitric Oxide Metabolites and Prevent Ultrastructural Alterations in Porcine Hyperscholesterolemia. Investigative Ophthalmology and Visual Science. 46 (4): 1140-1146, 2005.
  • Frei B et al. Ascorbate is an outstanding antioxidant in human blood plasma.  Proceedings of the National Academy of Sciences USA. 86(16):6377-6381, 1989.
  • Gardner, J., et al. Zinc Supplementation and Psychosocial Stimulation: Effects on the Development of Undernourished Jamaican Children. American Journal of Clinical Nutrition. 82: 399 – 405, 2005.
  • Hall, S. and Greendale, G.  The Relation of Dietary Vitamin C Intake to Bone Mineral Density: Results from the PEPI Study.  Calcified Tissue International. 63: 183-189, 1998.
  • Halterman, J., et al. Iron Deficiency and Cognitive Achievement among School-Aged Children and Adolescents in the United States. Pediatrics. 107: 1381 – 1386, 2001.
  • Henning S et al.  Glutathione blood levels and other oxidant defense indexes in men fed diets low in vitamin C.  Journal of Nutrition.  121:169-175, 1991.
  • Holick, M. Resurrection of Vitamin D Deficiency and Rickets. Journal of Clinical Investigation. 116: 2062-2072, 2006.
  • Holick, M. Vitamin D: Importance in the Prevention of Cancers, Type 1 Diabetes, Heart Disease, and Osteoporosis. American Journal of Clinical Nutrition. 79: 362 – 371, 2004.
  • James S et al. Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism. American Journal of Clinical Nutrition. 80(6):1611-7, 2004.
  • Johnston C et al. Vitamin C elevates red blood cell glutathione in healthy adults.  American Journal of Clinical Nutrition.  58(1):103-105, 1993.
  • Kelly G. Folates: supplemental forms and therapeutic applications. Alternative Medicine Review. 3:208-20, 1998. Review.
  • Kidd P. Autism, an extreme challenge to integrative medicine.  Part II: medical management. Alternative Medicine Review. 7(6):472-499, 2002.
  • Kimura,  M., et al.  Methylenetetrahydrofolate Reductase C677T Polymorphism, Folic Acid and Riboflavin are Important Determinants of Genome Stability in Cultured Human Lymphocytes. Journal of  Nutrition. 134(1):48-56, 2004.
  • Kirsch M et al. Ascorbate is a potent antioxidant against peroxynitrite-induced oxidation reactions. Evidence that ascorbate acts by re-reducing substrate radicals produced by peroxynitrite.  J Biol Chem.  275(22):16702-16708, 2000.
  • Kleijnen J and Knipschild P. Niacin and vitamin B6 in mental functioning: a review of controlled trials in humans. Biological Psychiatry. 29(9):931-41, 1991.
  • Kotsanis C et al. Autism – A multidisciplinary approach to treatment. Study Profile, DFW Ear, Nose & Throat Associates. Grapevine TX. No date given.
  • Kraus, A., et al. Supplementation with Vitamin C, Vitamin E or ß-Carotene Influences Osmotic Fragility and Oxidative Damage of Erythrocytes of Zinc-Deficient Rats. Journal of Nutrition. 127: 1290-1296, 1997.
  • Kuo C et al.  Ascorbic acid, an endogenous factor required for acetylcholine release from the synaptic vesicles.  Japan Journal of Pharmacology.  30(4):481-492, 1980.
  • Leggott, P., et al. Effects of Ascorbic Acid Depletion and Supplementation on Periodontal Health and Subgingival Microflora in Humans. Journal of Dental Research. 70: 1531-1536, 1991.
  • Lelord G et al.  Effects of pyridoxine and magnesium on autistic symptoms:  initial observations.  Journal of Autism Developmental Disorders.  11(2):219-229, 1981.
  • Lenton, Kevin J., et al.  Vitamin C Augments Lymphocyte Glutathione in Subjects with Ascorbate Deficiency. American Journal of Clinical Nutrition. 77: 189 – 195, 2003.
  • Levy A and Hyman S. Use of complementary and alternative treatments for children with autistic spectrum disorders is increasing. Pediatric Annals. 32:685-91, 2003.
  • Levy S et al. Novel treatments for autistic spectrum disorders. Mental Retardation and Developmental Disabilities Research Reviews. 11(2):131-42, 2005. Review.
  • LimeBack, H., et al.  The effects of Hypocalcemia/Hypophosphatemia on Porcine Bone and Dental Hard tissues in an Inherited Form of Type 1 Pseudo-Vitamin D Deficiency Rickets. Journal of Dental Research. 71:346-352, 1992.
  • Lonsdale D et al. Treatment of autism spectrum children with thiamine tetrahydrofurfuryl disulfide: A pilot study.  Neuroendocrinology Letters. 23(4):303-308, 2002.
  • Marlow M et al.  Decreased magnesium in the hair of autistic children.  Journal of Orthomolecular Psychiatry.  13(2):117-122, 1984.
  • Martineau J et al.  Vitamin B6, magnesium, and combined B6-Mg:  therapeutic effects in childhood autism.  Biological Psychiatry.  20(5):467-478, 1985.
  • Martineau J et al. Brief report: an open middle-term study of combined vitamin B6-magnesium in a subgroup of autistic children selected on their sensitivity to this treatment.  Journal of Autism and Developmental Disorders. 18:435-447, 1988.
  • Martineau J et al. Effects of vitamin B6 on averaged evoked potential in infantile autism.  Biological Psychiatry.  16(7):627-641, 1981.
  • Martineau J et al. Electrophysiological effects of fenfluramine or combined vitamin B6 and magnesium on children with autistic behavior. Developmental Medicine and Child Neurology. 31:728-736, 1989.
    Matkovic, V., et al.  Calcium Supplementation and Bone Mineral Density in Females from Childhood to Young Adulthood: A Randomized
    Controlled Trial. American Journal of Clinical Nutrition. 81: 175 – 188, 2005.
  • Matsuda, T. and Toda, T. Effects of Vitamin B6 on Dental Caries in Rats.  Journal of Dental Research.  46(6): 1460-1464, 1967.
  • McGinnis W. Oxidative stress in autism. Alternative Therapies in Health and Medicine. 10(6):22-36, 2004. Review.
  • Megson M. Is autism a G-alpha protein defect reversible with natural vitamin A?  Medical Hypotheses.  54(6):979-983, 2000.
  • Meisel, P., et al. Magnesium Deficiency is Associated with Periodontal Disease. Journal of Dental Research. 84(10): 937-941, 2005.
  • Methylcobalamin. Alternative Medicine Review. 3:461-3, 1998.
  • Meydani M.  Protective role of dietary vitamin E on oxidative stress in ageing.  Age.  15:89-93, 1992.
  • Misner, D., et al. Vitamin A Deprivation Results in Reversible Loss of Hippocampal Long-term Synaptic Plasticity. Proceedings of the National Academy of Sciences. 98(20): 11714-11719, 2001.
  • Moretti P et al. Cerebral folate deficiency with developmental delay, autism, and response to folinic acid. Neurology. 64(6):1088-90, 2005.
  • Mousain-Bosc M et al. Improvement of neurobehavioral disorders in children supplemented with magnesium-vitamin B6. Magnesium Research. 19(1):53-62, 2006.
  • Mousain-Bosc, M., et al. Magnesium, Vitamin B6 Intake Reduces Central Nervous System Hyperexcitability in Children. Journal of the American College of Nutrition.  23: 545S-548S, 2004.
  • Nanci, A., et al. Morphological and Immunocytochemical Analyses on the Effects of Diet-induced Hypocalcemia on Enamel Maturation in the Rat Incisor.  Journal of Histochemistry and Cytochemistry. 48(8): 1043-1057, 2000.
  • Numakawa Y et al.  Vitamin E protected cultured cortical neurons from oxidative stress-induced cell death through the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase.  Journal of Neurochemistry.  97(4):1191-1202, 2006.
  • Osendarp S et al. Effect of a 12-mo micronutrient intervention on learning and memory in well-nourished and marginally nourished school-aged children: 2 parallel, randomized, placebo-controlled studies in Australia and Indonesia. American Journal of Clinical Nutrition. 86(4):1082-93, 2007.
  • Outila, T., et al.  Vitamin D Status Affects Serum Parathyroid Hormone Concentrations during Winter in Female Adolescents: Associations with Forearm Bone Mineral Density.  American Journal of Clinical Nutrition. 74: 206 – 210, 2001.
  • Paleologos M et al. Cohort Study of Vitamin C Intake and Cognitive Impairment. American Journal of Epidemiology. 148(1):45-50, 1998.
  • Pfeiffer S et al. Efficacy of vitamin B6 and magnesium in the treatment of autism: a methodology review and summary of outcomes. Journal of Autism and Developmental Disorders. 25(5):481-93, 1995.
  • Pussinen, P., et al. Periodontitis Is Associated with a Low Concentration of Vitamin C in Plasma. Clinical and Vaccine Immunology. 10(5): 897 – 902, 2003.
  • Qing Shi, H., et al.  Host Nutritional Selenium Status as a Driving Force for Influenza Virus Mutations. The Federation of American Societies for Experimental Biology. Express Article published online, 2001.
  • Rahman, J., et al. Effects of Zinc Supplementation as Adjunct Therapy on the Systemic Immune Responses in Shigellosis. American Journal of Clinical Nutrition. 81:  495 – 502, 2005.
  • Raslova K., et al.  Effect of Diet and 677 C-->T 5, 10-Methylenetetrahydrofolate Reductase Genotypes on Plasma Homocyst(e)ine Concentrations in Slovak Adolescent Population. Physiological Research. 49(6): 651-8, 2000.
  • Riggs, K. M., et al.  Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study. American Journal of Clinical Nutrition.  63(3):306-314, 1996.
  • Rimland B et al. The effect of high doses of vitamin B6 on autistic children:  a double-blind cross-over study.  American Journal of Psychiatry.  135(4):472, 1978.
  • Rimland B. Controversies in the treatment of autistic children: vitamin and drug therapy. Journal of Child Neurology. 3 Suppl:S68-72, 1988.
  • Rimland B. Vitamin B6 (and magnesium) in the treatment of autism.  Autism Research Review International.  1(4), 1987.
  • Rimland B. Vitamin C in the Prevention and Treatment of Autism. Autism Research Review International. 12:3, 1998.
  • Rink, L. and Kirchner, H.  Zinc-Altered Immune Function and Cytokine Production. Journal of Nutrition. 130: 1407S-1411S, 2000.
  • Sasaki H et al.  Vitamin B12 improves cognitive disturbance in rodents fed a choline-deficient diet.  Pharmacology Biochemistry and Behavior.  43(2):635-639, 1992.
  • Sasazuki, S., et al. Effect of Vitamin C on Common Cold: Randomized Controlled Trial.  European Journal of Clinical Nutrition.  60: 9-17, 2006.
  • Sedgh, G., et al. Dietary Vitamin A Intake and Nondietary Factors Are Associated with Reversal of Stunting in Children. Journal of Nutrition. 130: 2520-2526, 2000.
  • Slyshenkov V et al.  Pantothenic acid and pantothenol increase biosynthesis of glutathione by boosting cell energetics.  FEBS Lett.  569(1-3):169-172, 2004.
  • Taylor, A, et al. Rat Intestinal Vitamin D-dependent Calcium-binding Protein: Immunocytochemical Localization in Incisor Ameloblasts.  Journal of Dental Research.  63(2): 94-96, 1984.
  • Thiamine - Monograph.  Alternative Medicine Review.  8(1):59-62, 2003.
  • Tylavsky, F., et al. Fruit and Vegetable Intakes are an Independent Predictor of Bone Size in Early Pubertal Children. American Journal of Clinical Nutrition. 79: 311 – 317, 2004.
    Uauy, R., et al. Essentiality of Copper in Humans. American Journal of Clinical Nutrition. 67:  952 – 959, 1998.
  • Udomkesmalee, E., et al. Effect of Vitamin A and Zinc Supplementation on the Nutriture of Children in Northeast Thailand. American Journal of Clinical Nutrition. 56: 50 – 57, 1992.
  • Valero, M., et al. Vitamin C Is Associated with Reduced Risk of Cataract in a Mediterranean Population. Journal of Nutrition. 132: 1299-1306, 2002.
  • Van Stuijvenberg, E., et al. Effect of Iron-, Iodine-, and ß-carotene–Fortified Biscuits on the Micronutrient Status of Primary School Children: a Randomized Controlled Trial. American Journal of Clinical Nutrition. 69:  497 – 503, 1999.
  • Vatanparast, H., et al.  Positive Effects of Vegetable and Fruit Consumption and Calcium Intake on Bone Mineral Accrual in Boys during Growth from Childhood to Adolescence: the University of Saskatchewan Pediatric Bone Mineral Accrual Study.  American Journal of Clinical Nutrition.  82: 700-706, 2005.
  • Villamor, E. and Fawzi, W. Effects of Vitamin A Supplementation on Immune Response and Correlation with Clinical Outcomes. Clinical Microbiology Reviews. 18: 446-464, 2005.
  • Vitamin B6 (pyridoxine and pyridoxal 5'-phosphate) - monograph. Alternative Medicine Review. 6:87-92, 2001. Review.
  • Werbach M.  Nutritional treatments for autism - nutritional influences on illness.  Townsend Letter for Doctors and Patients.  October 2003.
  • Whiting, S., et al. Dietary Protein, Phosphorus and Potassium Are Beneficial to Bone Mineral Density in Adult Men Consuming Adequate Dietary Calcium. Journal of the American College of Nutrition.  21: 402-409, 2002.
  • Yao Y et al. Altered vascular phenotype in autism: correlation with oxidative stress. Archives of Neurology. 63(8):1161-4, 2006., Div. of  •  Independent Market America Distributor  •  Most products ship within 24 hours

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